New drug to generate self-destruct process in lung cancer cells


Washington: A drug combination has been discovered which can trigger the self-destruct process in lung cancer cells.

Using lung cancer cells and mice the Cancer Research UK team, based at the UCL Cancer Institute scientists, showed that the combination of two drugs, called TRAIL and a CDK9 inhibitor, altered the molecular switches in the cell suicide process, hence forcing the cancer cells to self-destruct.

Lead researcher, Cancer Research UK scientist Professor Henning Walczak from the UCL Cancer Institute, said that igniting the fuse that caused lung cancer cells to self-destruct could pave the way to a completely new treatment approach.

Nell Barrie, senior science information manager at Cancer Research UK, added that understanding and targeting these processes would help move closer to the goal of 3 out of 4 people beating cancer within the next 20 years.

The research is due to be presented at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s